A young girl, Chantico, sets out an adventure to recover her parents after they are sacrificed to be food to the gods. The young girl encounters many different characters on her journey. The Bone Collector is a spirit which encompasses both good and bad traits and a guides for her different tasks. Chantico's initial task is to steal a talisman from a temple, which allows objects to be brought between the spirit and real world. While she is stealing the talisman, a temple priest catches her. After hearing Chantico’s story he offers it to her to help her on her mission.
The Spirit path is a deserted land where no one dares to walk. Armed with a stick and the talisman, she fights off animals and completes challenges and puzzles along the way. Chantico later comes across a mask which allows her to see into the spirit world. When Chanitco wears the mask, more ‘doorways’ begin to open up for her and the player into different areas. Now the girl comes across more puzzles, which involve using both what appears in the spirit and real world.
The talisman allows her to transport objects between the two worlds. The talisman also allows her to cross over large crevasses, rivers etc, becoming almost like a teleportation device. Chantico is unable to kill spirits in the spirit world though, so she must avoid them at all costs. Spirits usually come in the form of dead animals from the real world which are now evil and twisted.
When Chantico kills a real world creature, she is able to collect its spirit or 'Orb' which may help to rejuvanate her in the form of strength, healt, etc. Throughout the game Chantico will also come across new weapons, such as a dagger and a razor sword or staff. This staff will finally allow her to kill both spirits and living creatures.
Through the journey she fights certain bosses with the guidance of the Bone Collector. However, although the Bone Collector at first seems to be on Chantico's side, during the last stage of the game he turns against her. We find that he was leading her down the spirit path only due to wanting to later collect her bones. Chantico fights against him and defeats him, reaching the end of the path. The priest from the temple appears once again, stealing the talisman away from the girl.
We now discover that the Priest is a spirit that has been sent by the Gods. He has been sent with a message that humans must sacrifice more people as the Gods require more blood to survive. The priest has been on earth for 300 years and has grown sick of the disgusting state of the earth. He was unable to track the spirit path so used the girl to do it as a means of returning home. The priest combines himself with the talisman and transforms into a giant twisted half human, half spirit boss. She defeats the Priest, the final boss of the game and manages to save her parents in time.
